Selected Publications

Aguglia GA, Coyne CB, Dermody TS, Williams JV, and Freeman MC. “Contemporary Enterovirus-D68 Isolates Infect Human Spinal Cord Organoids.” mBio. 2023 Aug 3;e0105823. http://doi: 10.1128/mbio.01058-23.

Lu E, Sinha A, Freeman MC. “Clinical Progress Note: Enterovirus D68 and Acute Flaccid Myelitis.” Journal of Hospital Medicine. 2023 Mar 20;. doi: 10.1002/jhm.13085. [Epub ahead of print] PubMed PMID: 36938975.

Freeman MC. “Setting the Stage for the Next Great Vaccine Success Story.” mBio, 2022, e00457-22. https://doi.org/10.1128/mbio.00457-22.

Freeman MC*, Lazzara A*, Lennon T, McAteer J, Pease M, Sefcik R, Radovic-Stakic A, Milstone AM, Nowalk A, and Trent M. “Gonococcal Infection and Ventriculoperitoneal Shunts.” Sexually Transmitted Diseases 49, no. 12 (December 2022): 838–40. https://doi.org/10.1097/OLQ.0000000000001671.

Freeman MC, Freeman TJ, Iagnemma J, Rasmussen J, Heidenreich K, Wells A, Hoberman A, and Mitchell SL. “Performance of the Sofia SARS-CoV-2 Rapid Antigen Test in Symptomatic and Asymptomatic Pediatric Patients.” Journal of the Pediatric Infectious Diseases Society 11, no. 9 (September 29, 2022): 417–21. https://doi.org/10.1093/jpids/piac035.

Mitchell SL, Orris S, Freeman T, Freeman MC, Adam M, Axe M, Gribschaw J, Suyama J, Hoberman A, and Wells A. “Performance of SARS-CoV-2 Antigen Testing in Symptomatic and Asymptomatic Adults: A Single-Center Evaluation.” BMC Infectious Diseases 21, no. 1 (October 18, 2021): 1071. https://doi.org/10.1186/s12879-021-06716-1.

Gaietto K, Freeman MC, DiCicco LA, Rauenswinter S, Squire JR, Aldewereld Z, Iagnemma J, et al. “Asthma as a Risk Factor for Hospitalization in Children with COVID‐19: A Nested Case‐Control Study.” Pediatric Allergy and Immunology, 2021. https://doi.org/10.1111/pai.13696.

Rapsinski GJ*, Freeman MC*, Haidar G, Belle SH, Hasskamp JH, and Wheeler SE. “Pediatric SARS-CoV-2 Seroprevalence during Mitigation Procedures in Southwestern Pennsylvania.” Journal of Clinical Virology Plus 1, no. 3 (September 2021): 100026. https://doi.org/10.1016/j.jcvp.2021.100026.

Freeman MC, Wells AI, Ciomperlik-Patton J, Myerburg MM, Yang L, Konopka-Anstadt J, and Coyne C. “Respiratory and Intestinal Epithelial Cells Exhibit Differential Susceptibility and Innate Immune Responses to EV-D68.” ELife 10 (2021): e66687. https://doi.org/10.7554/elife.66687.

Geisler D, Freeman MC, Rapsinski GJ, and Wheeler SE. “Unexpected False-Positive Rates in Pediatric SARS-CoV-2 Serology Using the EUROIMMUN Anti-SARS-CoV-2 ELISA IgG Assay.” American Journal of Clinical Pathology 155, no. 6 (May 18, 2021): 773–75. https://doi.org/10.1093/ajcp/aqab033.

Freeman MC, Gaietto K, DiCicco LA, Rauenswinter S, Squire JR, Aldewereld Z, Rapsinski G, Iagnemma J, Campfield B, Wolfson D, Kazmerski T, Forno E. “A Comprehensive Clinical Description of Pediatric SARS-CoV-2 Infection in Western Pennsylvania.” MedRxiv, December 16, 2020, 2020.12.14.20248192. https://doi.org/10.1101/2020.12.14.20248192.

Freeman MC*, Rapsinski GJ*, Zilla ML, and Wheeler SE. “Immunocompromised Seroprevalence and Course of Illness of SARS-CoV-2 in One Pediatric Quaternary Care Center.” Journal of the Pediatric Infectious Diseases Society 10, no. 4 (April 30, 2021): 426–31. https://doi.org/10.1093/jpids/piaa123.

Freeman MC, Haddadin Z, Lawrence L, Piya B, Krishnaswami S, Faouri S, Shehabi A, Williams JV, Khuri‐Bulos N, and Halasa N. “Utility of RSV Rapid Diagnostic Assays in Hospitalized Children in Amman, Jordan.” Journal of Medical Virology, 2020. https://doi.org/10.1002/jmv.26546.

Freeman MC, Mitchell S, Ibrahim J, and Williams JV.“Neonatal Toxic Shock Syndrome–Like Exanthematous Disease in North America.” Journal of the Pediatric Infectious Diseases Society 351 (September 2019): 1614–2. https://doi.org/10.1093/jpids/piz060.

Cramer N, Munjal N, Ware D, Ramgopal S, Simon D, Freeman MC, Michaels MG, Stem C, Thakkar K, Williams JV, Panigraphy A, Neville DNW, Owusu-Ansah S. “New Cluster of Acute Flaccid Myelitis in Western Pennsylvania.” Annals of Emergency Medicine 74, no. 4 (October 2019): 503–8. https://doi.org/10.1016/j.annemergmed.2019.01.024.

Freeman MC, Coyne CB, Green M, Williams JV, and Silva LA. “Emerging Arboviruses and Implications for Pediatric Transplantation: A Review.” Pediatric Transplantation 23, no. 1 (October 2018): e13303-12. https://doi.org/10.1111/petr.13303.

Wang L, Shi W, Joyce MG, Modjarrad K, Zhang Y, Leung K, Lees CR, Zhou T, Yassine HM, Kanekiyo M, Yang Z, Chen X, Becker M, Freeman MC, Vogel L, Johnson J, Olinger G, Todd JP, Bagci U, Solomaon J, Mollura DJ, Hensley L, Jahrling P, Denison MR, Rao SS, Subbarao K, Kwong PD, Mascola JR, Kong W, Graham, BS. “Evaluation of Candidate Vaccine Approaches for MERS-CoV.” Nature Communications 6, no. 1 (1AD): 1–11. https://doi.org/10.1038/ncomms8712.

Freeman MC, Peek CT, Becker MM, Smith EC, and Denison MR. “Coronaviruses Induce Entry-Independent, Continuous Macropinocytosis.” mBio 5, no. 4 (July 2014): e01340-14-e01340-14. https://doi.org/10.1128/mbio.01340-14.

Freeman MC, Graham RL, Lu X, Peek CT, and Denison MR. “Coronavirus Replicase-Reporter Fusions Provide Quantitative Analysis of Replication and Replication Complex Formation.” Journal of Virology 88, no. 10 (May 2014): 5319–27. https://doi.org/10.1128/JVI.00021-14.

*denotes co-first author